C type lectin domain family 9, member A
C-type lectin domain family 9 member A
CLC9A_HUMAN
CLEC9A
DNGR1
HEEE9341
PRO34046
UNQ9341.
Product description
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Immunogen
KLH conjugated synthetic peptide derived from human CLEC9A 101-200/241
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
C type lectin domain family 9 member A
C-type lectin domain family 9 member A
CLC9A_HUMAN
CLEC9A
DNGR1
HEEE9341
PRO34046
UNQ9341.
Fig1: Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- CLEC9A (ER1906-42) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 35 kD
Positive Control
In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.