Application
Fig1: Sample: Uterus (Mouse) Lysate at 40 ug Primary: Anti- CSNK1G2 (ER1906-77) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 49 kD| Product Name | CSNK1G2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Casein kinase 1, gamma 2 KC1G2_HUMAN Casein kinase I isoform gamma 2 CK1g2 CKI gamma 2 CSNK1G 2 CSNK1G2. |
| Product description | Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. |
| Immunogen | KLH conjugated synthetic peptide derived from human CSNK1G2 211-320/415 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatChickenDogPigCowHorseRabbit |
| Concentration | 1mg/ml |
| Alternative Names | Casein kinase 1 gamma 2 KC1G2_HUMAN Casein kinase I isoform gamma 2 CK1g2 CKI gamma 2 CSNK1G 2 CSNK1G2. |
|---|---|
| Molecular Weight(MW) | 47 KDa |
| Cellular Localization | Cytoplasm. |
| SwissProt ID | P78368 |
|---|
Application
Fig1: Sample: Uterus (Mouse) Lysate at 40 ug Primary: Anti- CSNK1G2 (ER1906-77) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 49 kD| Positive Control | Testis. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
