Application
Fig1: Sample: HepG2(Human) Cell Lysate at 40 ug Primary: Anti- CXCR1 (ER1906-86) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 40 kD| Product Name | CXCR1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C C C C CKR 1 CCCKR1 CD 181 CD128 CD181 CDw128a Chemokine (C X C motif) receptor 1 Chemokine (C X C) receptor 1 Chemokine receptor 1 CKR 1 CMKAR1 CXCR 1 High affinity interleukin 8 receptor A IL 8 receptor type 1 IL 8R A IL-8RA IL8 receptor IL8 receptor type 1 IL8R1 IL8RA IL8RBA Interleukin 8 receptor alpha Interleukin 8 receptor type 1. Interleukin 8 receptor type A CXCR1_HUMAN C-C CD181 CKR-1 IL8R1 CDw128a C-C-CKR-1. |
| Product description | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. |
| Immunogen | KLH conjugated synthetic peptide derived from human CXCR1 186-280/350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC-P |
| WB:1:500-2000: IHC-P:1:400-800: |
|
| Species Reactivity | HumanMouseRatDogCowRabbit |
| Concentration | 1mg/ml |
| Alternative Names | C C C C CKR 1 CCCKR1 CD 181 CD128 CD181 CDw128a Chemokine (C X C motif) receptor 1 Chemokine (C X C) receptor 1 Chemokine receptor 1 CKR 1 CMKAR1 CXCR 1 High affinity interleukin 8 receptor A IL 8 receptor type 1 IL 8R A IL-8RA IL8 receptor IL8 receptor type 1 IL8R1 IL8RA IL8RBA Interleukin 8 receptor alpha Interleukin 8 receptor type 1. Interleukin 8 receptor type A CXCR1_HUMAN C-C CD181 CKR-1 IL8R1 CDw128a C-C-CKR-1. |
|---|---|
| Molecular Weight(MW) | 40 KDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | P25024 |
|---|
Application
Fig1: Sample: HepG2(Human) Cell Lysate at 40 ug Primary: Anti- CXCR1 (ER1906-86) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 40 kD| Positive Control | Rat colitis tissue, HepG2 Cell Lysate. |
|---|---|
| Application Notes | WB:1:500-2000: IHC-P:1:400-800: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
