NDRD
RRD
AI043103
AI790593
Carbonyl reductase
CR
D14Ucla2
Dehydrogenase/reductase SDR family member 4
Dhrs4
DHRS4_HUMAN
humNRDR antibody NADPH dependent carbonyl reductase/NADP retinol dehydrogenase
NADPH dependent retinol dehydrogenase/reductase
NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase
NADPH-dependent retinol dehydrogenase/reductase
NRDR
Peroxisomal short chain alcohol dehydrogenase
Peroxisomal short-chain alcohol dehydrogenase
PHCR
PRO1800
PSCD
SCAD-SRL
SCADSRL
Short chain dehydrogenase/reductase family member 4
Short-chain dehydrogenase/reductase family member 4
UNQ851.
Product description
Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).
Immunogen
KLH conjugated synthetic peptide derived from human DHRS4 161-278/278
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
NDRD
RRD
AI043103
AI790593
Carbonyl reductase
CR
D14Ucla2
Dehydrogenase/reductase SDR family member 4
Dhrs4
DHRS4_HUMAN
humNRDR antibody NADPH dependent carbonyl reductase/NADP retinol dehydrogenase
NADPH dependent retinol dehydrogenase/reductase
NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase
NADPH-dependent retinol dehydrogenase/reductase
NRDR
Peroxisomal short chain alcohol dehydrogenase
Peroxisomal short-chain alcohol dehydrogenase
PHCR
PRO1800
PSCD
SCAD-SRL
SCADSRL
Short chain dehydrogenase/reductase family member 4
Short-chain dehydrogenase/reductase family member 4
UNQ851.
Molecular Weight(MW)
30 KDa
Cellular Localization
Peroxisome. Note=Isoform 1 is peroxisomal, while isoform 4 is not. ;Isoform 7: Nucleus.
Fig1: Sample:
Liver (Mouse) Lysate at 40 ug
Heart (Mouse) Lysate at 40 ug
Primary: Anti- DHRS4 (ER1907-44)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30kD
Observed band size: 34kD
Positive Control
Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.