Application
Fig1: Sample: bone (rat)Lysate at 40 ug Primary: Anti- MRPL32 (ER1908-82)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27kD Observed band size: 27kD| Product Name | FGF23 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADHR FGF-23 Fgf23 FGF 23 FGF23_HUMAN Fibroblast growth factor 23 Fibroblast growth factor 23 N-terminal peptide Fibroblast growth factor 23 precursor HPDR2 HYPF Phosphatonin PHPTC Tumor derived hypophosphatemia inducing factor Tumor-derived hypophosphatemia-inducing factor. |
| Product description | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. |
| Immunogen | KLH conjugated synthetic peptide derived from human Fibroblast growth factor 23 21-120/251 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigCowHorseRabbitSheepGuinea Pig |
| Concentration | 1mg/ml |
| Alternative Names | ADHR FGF-23 Fgf23 FGF 23 FGF23_HUMAN Fibroblast growth factor 23 Fibroblast growth factor 23 N-terminal peptide Fibroblast growth factor 23 precursor HPDR2 HYPF Phosphatonin PHPTC Tumor derived hypophosphatemia inducing factor Tumor-derived hypophosphatemia-inducing factor. |
|---|---|
| Molecular Weight(MW) | 27 KDa |
| Cellular Localization | Secreted. Note=Secretion is dependent on O-glycosylation. |
| SwissProt ID | Q9GZV9 |
|---|
Application
Fig1: Sample: bone (rat)Lysate at 40 ug Primary: Anti- MRPL32 (ER1908-82)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27kD Observed band size: 27kD| Positive Control | Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts). |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
