Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Cerebrum (Rat) Lysate at 40 ug Primary: Anti- FKBP38 (ER1908-88) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 50 kD| Product Name | FKBP38 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 38 kDa FK 506 binding protein homolog 38 kDa FK506-binding protein 38 kDa FKBP 38kDa antibody FK506 binding protein 8 FK506 binding protein 8, 38kDa FK506 binding protein, 38kDa FK506-binding protein 8 FKBP 38 FKBP-38 FKBP-8 FKBP8 FKBP8_HUMAN FKBPR38 hFKBP38 Peptidyl-prolyl cis-trans isomerase FKBP8 PPIase FKBP8 Rotamase Sam11. |
| Product description | Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. |
| Immunogen | KLH conjugated synthetic peptide derived from human FKBP38 255-350/412 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatChickenDogCowHorse |
| Concentration | 1mg/ml |
| Alternative Names | 38 kDa FK 506 binding protein homolog
38 kDa FK506-binding protein
38 kDa FKBP
38kDa antibody FK506 binding protein 8
FK506 binding protein 8 38kDa FK506 binding protein 38kDa FK506-binding protein 8 FKBP 38 FKBP-38 FKBP-8 FKBP8 FKBP8_HUMAN FKBPR38 hFKBP38 Peptidyl-prolyl cis-trans isomerase FKBP8 PPIase FKBP8 Rotamase Sam11. |
|---|---|
| Molecular Weight(MW) | 46 KDa |
| Cellular Localization | Mitochondrion membrane; Single-pass membrane protein; Cytoplasmic side (By similarity). |
| SwissProt ID | Q14318 |
|---|
Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Cerebrum (Rat) Lysate at 40 ug Primary: Anti- FKBP38 (ER1908-88) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 50 kD| Positive Control | Widely expressed. Highest levels seen in the brain. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
