4930573H17Rik
B230215M10Rik
GAS 41
Gas41
glioma amplified sequence 41
Glioma-amplified sequence 41
glioma-amplified sequence-41
gliomaamplified sequence 41
gliomaamplified sequence41
NUBI 1
NuBI-1
NuBI1
NuMA binding protein 1
NuMA-binding protein 1
YAF9
YEATS domain containing 4
YEATS domain containing4
YEATS domain-containing protein 4
YEATS4
YETS4_HUMAN.
Product description
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Immunogen
KLH conjugated synthetic peptide derived from human GAS41 151-227/227
Fig1: Sample: Spleen (Mouse) Lysate at 40 ug
Primary: Anti-GAS41(ER1909-40) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
Positive Control
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.