Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-KCNJ3 (ER1909-61) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 60 kD| Product Name | GIRK1/KCNJ3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | inwardly rectifying subfamily J member 3 G protein activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 1 GIRK-1 Inward rectifier K(+) channel Kir3.1 Inwardly rectifying potassium channel KIR3.1 IRK3 IRK3_HUMAN Kcnf3 Kcnj3 KGA KGB1 Kir3.1 Potassium channel Potassium channel, inwardly rectifying subfamily J member 3 Potassium inwardly-rectifying channel, subfamily J, member 3. |
| Product description | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. |
| Immunogen | KLH conjugated synthetic peptide derived from human GIRK1 81-180/501 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigCowRabbitGuinea Pig |
| Concentration | 1mg/ml |
| Alternative Names | inwardly rectifying subfamily J member 3
G protein activated inward rectifier potassium channel 1
G protein-activated inward rectifier potassium channel 1
GIRK-1
Inward rectifier K(+) channel Kir3.1
Inwardly rectifying potassium channel KIR3.1
IRK3
IRK3_HUMAN
Kcnf3
Kcnj3
KGA
KGB1
Kir3.1
Potassium channel
Potassium channel inwardly rectifying subfamily J member 3 Potassium inwardly-rectifying channel subfamily J member 3. |
|---|---|
| Molecular Weight(MW) | 55 KDa |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| SwissProt ID | P48549 |
|---|
Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-KCNJ3 (ER1909-61) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 60 kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
