Application
Fig1: Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Glucose 6 phosphatase 2 (ER1909-71) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD| Product Name | Glucose 6 phosphatase 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | G 6 Pase 2 G 6 Pase2 G6Pase 2 G6Pase2 G6PC 2 G6pc rs G6pcrs Glucose 6 phosphatase 2 Glucose 6 phosphatase, catalytic, 2 Glucose 6 phosphatase, catalytic, related Glucose 6 phosphate catalytic 2 Islet specific G6CP related protein Islet specific glucose 6 phosphatase Islet specific glucose 6 phosphatase catalytic subunit related protein G6PC2_HUMAN. |
| Product description | IGRP (islet specific glucose 6 phosphatase catalytic subunit related protein), also known as G6PC2, belongs to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyses the hydrolysis of glucose-6-phosphate. This hydrolysis is the terminal step in gluconeogenic and glycogenolytic pathways, and allows the release of glucose into the bloodstream. IGRP is found in pancreatic islets and does not exhibit phosphohydrolase activity. However, it is a major target of cell-mediated autoimmunity in diabetes. |
| Immunogen | KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP 31-130/355 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatCowHorseRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | G 6 Pase 2
G 6 Pase2
G6Pase 2
G6Pase2
G6PC 2
G6pc rs
G6pcrs
Glucose 6 phosphatase 2
Glucose 6 phosphatase catalytic 2 Glucose 6 phosphatase catalytic related Glucose 6 phosphate catalytic 2 Islet specific G6CP related protein Islet specific glucose 6 phosphatase Islet specific glucose 6 phosphatase catalytic subunit related protein G6PC2_HUMAN. |
|---|---|
| Molecular Weight(MW) | 41 KDa |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| SwissProt ID | Q9NQR9 |
|---|
Application
Fig1: Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Glucose 6 phosphatase 2 (ER1909-71) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD| Positive Control | Specifically expressed in pancreas and also detected to a lower extent in testis. Expressed by most islet cells in the pancreas (at protein level). |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
