Application
Fig1: Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-GPR120 (ER1909-96) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD| Product Name | GPR120 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids. |
| Immunogen | KLH conjugated synthetic peptide derived from human G protein coupled receptor 120 21-120/377 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | CowDogHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Alternative Names | G protein coupled receptor 120 GPCR GPR120 G protein coupled receptor 129 G protein coupled receptor GT01 G protein coupled receptor PGR 4 G protein coupled receptor PGR4 G-protein coupled receptor 120 G-protein coupled receptor 129 G-protein coupled receptor GT01 G-protein coupled receptor PGR4 GPR 120 GPR 129 GPR120 GPR129 GT01 HGNC:19345 MGC119984 O3FA1_HUMAN O3FAR1 Omega-3 fatty acid receptor 1 PGR 4 PGR4 GPCR120. |
|---|---|
| Molecular Weight(MW) | 42 KDa |
| Cellular Localization | Cell membrane. Colocalized with ARRB2 following DHA treatment. |
| SwissProt ID | Q5NUL3 |
|---|
Application
Fig1: Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-GPR120 (ER1909-96) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD| Positive Control | Abundant expression in the intestinal tract. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
