Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-HCN4 (ER1910-38) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 129 kD Observed band size: 129 kD| Product Name | HCN4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HCN 4 Hyperpolarization activated cyclic nucleotide gated potassium channel 4 Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 4 Hyperpolarization activated Cyclic Nucleotide-gated channel 4 HCN4_HUMAN. |
| Product description | Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP. May mediate responses to sour stimuli. |
| Immunogen | KLH conjugated synthetic peptide derived from human HCN4 501-600/1203 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC-P |
| WB:1:500-2000: IHC-P:1:400-800: |
|
| Species Reactivity | HumanMouseRatPigCowRabbit |
| Concentration | 1mg/ml |
| Alternative Names | HCN 4 Hyperpolarization activated cyclic nucleotide gated potassium channel 4 Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 4 Hyperpolarization activated Cyclic Nucleotide-gated channel 4 HCN4_HUMAN. |
|---|---|
| Molecular Weight(MW) | 129 KDa |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| SwissProt ID | Q9Y3Q4 |
|---|
Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-HCN4 (ER1910-38) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 129 kD Observed band size: 129 kD| Positive Control | Highly expressed in thalamus, testis and in heart, both in ventricle and atrium. Detected at much lower levels in amygdala, substantia nigra, cerebellum and hippocampus. |
|---|---|
| Application Notes | WB:1:500-2000: IHC-P:1:400-800: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
