Application
Fig1: Sample: U937(Human) Cell Lysate at 30 ug Primary: Anti- HES6 (ER1910-52) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 26 kD| Product Name | HES6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | bHLHb41 bHLHc23 C HAIRY1 Class B basic helix-loop-helix protein 41 Hairy and enhancer of split 6 HES 6 Transcription cofactor HES6 HES6_HUMAN. |
| Product description | HES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully. |
| Immunogen | KLH conjugated synthetic peptide derived from human HES6 1-80/224 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatPigCow |
| Concentration | 1mg/ml |
| Alternative Names | bHLHb41 bHLHc23 C HAIRY1 Class B basic helix-loop-helix protein 41 Hairy and enhancer of split 6 HES 6 Transcription cofactor HES6 HES6_HUMAN. |
|---|---|
| Molecular Weight(MW) | 24 KDa |
| Cellular Localization | Nuclear |
| SwissProt ID | Q96HZ4 |
|---|
Application
Fig1: Sample: U937(Human) Cell Lysate at 30 ug Primary: Anti- HES6 (ER1910-52) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 26 kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
