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HSD11B2

Catalog Number:OM630254
OM630254
Discount Price
OM630254-100ul
1~2 Week
100ul
OM630254-50ul
50ul
OM630254-20ul
20ul
1~2 Week
Product Profile
Product Name HSD11B2
Antibody Type Primary Antibodies
Antigen Alias Corticosteroid 11 beta dehydrogenase isozyme 2 11 beta HSD2 11 beta hydroxysteroid dehydrogenase type 2 11 DH2 AME AME1 HSD11K HSD2 Hydroxysteroid 11 beta dehydrogenase 2 Hydroxysteroid 11 beta dehydrogenase isoenzyme 2 NAD dependent 11 beta hydroxysteroid dehydrogenase SDR9C3 Short chain dehydrogenase/reductase family 9C, member 3.
Product description Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Immunogen KLH conjugated synthetic peptide derived from human HSD11B2 151-250/405
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-2000:
Species Reactivity HumanMouseRatDogHorse
Concentration 1mg/ml
Target Information
Alternative Names Corticosteroid 11 beta dehydrogenase isozyme 2 11 beta HSD2 11 beta hydroxysteroid dehydrogenase type 2 11 DH2 AME AME1 HSD11K HSD2 Hydroxysteroid 11 beta dehydrogenase 2 Hydroxysteroid 11 beta dehydrogenase isoenzyme 2 NAD dependent 11 beta hydroxysteroid dehydrogenase SDR9C3 Short chain dehydrogenase/reductase family 9C
member 3.
Molecular Weight(MW) 45 KDa
Cellular Localization Microsome. Endoplasmic reticulum.
Database Links
SwissProt ID P80365
Application

Application

Fig1: Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-HSD11B2 (ER1910-87) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 48 kD
Positive Control Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.
Application Notes WB:1:500-2000:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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