Corticosteroid 11 beta dehydrogenase isozyme 2
11 beta HSD2
11 beta hydroxysteroid dehydrogenase type 2
11 DH2
AME
AME1
HSD11K
HSD2
Hydroxysteroid 11 beta dehydrogenase 2
Hydroxysteroid 11 beta dehydrogenase isoenzyme 2
NAD dependent 11 beta hydroxysteroid dehydrogenase
SDR9C3
Short chain dehydrogenase/reductase family 9C, member 3.
Product description
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Immunogen
KLH conjugated synthetic peptide derived from human HSD11B2 151-250/405
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRatDogHorse
Concentration
1mg/ml
Target Information
Alternative Names
Corticosteroid 11 beta dehydrogenase isozyme 2
11 beta HSD2
11 beta hydroxysteroid dehydrogenase type 2
11 DH2
AME
AME1
HSD11K
HSD2
Hydroxysteroid 11 beta dehydrogenase 2
Hydroxysteroid 11 beta dehydrogenase isoenzyme 2
NAD dependent 11 beta hydroxysteroid dehydrogenase
SDR9C3
Short chain dehydrogenase/reductase family 9C member 3.
Fig1: Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti-HSD11B2 (ER1910-87) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 48 kD
Positive Control
Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.