ATP:D-hexose 6 phosphotransferase
FGQTL3
GCK
GK
GLK
Glucokinase
Hexokinase D
Hexokinase D, pancreatic isozyme
Hexokinase type IV
Hexokinase-4
Hexokinase-D
HHF3
HK IV
HK4
HXK4_HUMAN
HXKP
LGLK
MODY2.
Product description
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Immunogen
KLH conjugated synthetic peptide derived from human IGLK 101-200/465
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRatChickenDogPigCowHorseRabbit
Concentration
1mg/ml
Target Information
Alternative Names
ATP:D-hexose 6 phosphotransferase
FGQTL3
GCK
GK
GLK
Glucokinase
Hexokinase D
Hexokinase D pancreatic isozyme
Hexokinase type IV
Hexokinase-4
Hexokinase-D
HHF3
HK IV
HK4
HXK4_HUMAN
HXKP
LGLK
MODY2.
Fig1: Sample:Heart (Mouse) Lysate at 40 ug
Primary: Anti-IGLK (ER1911-16)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52kD
Observed band size: 52kD
Positive Control
Isoform 1 is expressed in pancreas. Isoform 2 and isoform 3 is expressed in liver.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.