KCNV1
KCNV1_HUMAN
Neuronal potassium channel alpha subunit HNKA
Potassium voltage gated channel subfamily V member 1
Potassium voltage-gated channel subfamily V member 1
Voltage gated potassium channel subunit Kv8.1
Voltage-gated potassium channel subunit Kv8.1
Product description
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
Immunogen
KLH conjugated synthetic peptide derived from human KCNT1 251-350/500
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRatDogPigCowHorseRabbitSheep
Concentration
1mg/ml
Target Information
Alternative Names
KCNV1
KCNV1_HUMAN
Neuronal potassium channel alpha subunit HNKA
Potassium voltage gated channel subfamily V member 1
Potassium voltage-gated channel subfamily V member 1
Voltage gated potassium channel subunit Kv8.1
Voltage-gated potassium channel subunit Kv8.1
Molecular Weight(MW)
56 KDa
Cellular Localization
Cell membrane. Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2.
Fig1: Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-KCNV1 (ER1911-76) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD
Positive Control
Detected in brain.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.