Application
Fig1: Sample: Bone(Rat) Cell Lysate at 40 ug Thymus(Rat) Cell Lysate at 40 ug Primary: Anti-LRRC33 (ER1912-49) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 74 kD Observed band size: 74 kD| Product Name | LRRC33 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELLP3030 GARPL1 NRROS_HUMAN Leucine rich repeat containing protein 33 Lrcc33 UNQ3030. |
| Product description | Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex.; May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. |
| Immunogen | KLH conjugated synthetic peptide derived from human LRRC33 501-600/692 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICC/IF |
| WB:1:500-2000: IF:1:100-500: ICC:1:100-500: |
|
| Species Reactivity | HumanMouseRatRabbit |
| Concentration | 1mg/ml |
| Alternative Names | ELLP3030 GARPL1 NRROS_HUMAN Leucine rich repeat containing protein 33 Lrcc33 UNQ3030. |
|---|---|
| Molecular Weight(MW) | 74 KDa |
| Cellular Localization | Membrane; Single pass type I membrane protein. |
| SwissProt ID | Q86YC3 |
|---|
Application
Fig1: Sample: Bone(Rat) Cell Lysate at 40 ug Thymus(Rat) Cell Lysate at 40 ug Primary: Anti-LRRC33 (ER1912-49) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 74 kD Observed band size: 74 kD| Positive Control | Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen. |
|---|---|
| Application Notes | WB:1:500-2000: IF:1:100-500: ICC:1:100-500: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
