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MMP7

Catalog Number:OM630471
OM630471
Discount Price
OM630471-100ul
1~2 Week
100ul
OM630471-50ul
50ul
OM630471-20ul
20ul
1~2 Week
Product Profile
Product Name MMP7
Antibody Type Primary Antibodies
Antigen Alias Matrilysin Matrilysin uterine Matrin Matrix Metalloproteinase 7 MMP-7 MMP 7 MMP7 MPSL1 PUMP 1 Pump 1 protease PUMP1 Uterine Matrilysin Uterine metalloproteinase MMP7_HUMAN.
Product description This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.
Immunogen KLH conjugated synthetic peptide derived from human MMP7 151-250/269
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC-P
WB:1:500-2000:
IHC-P:1:400-800:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names Matrilysin Matrilysin uterine Matrin Matrix Metalloproteinase 7 MMP-7 MMP 7 MMP7 MPSL1 PUMP 1 Pump 1 protease PUMP1 Uterine Matrilysin Uterine metalloproteinase MMP7_HUMAN.
Molecular Weight(MW) 30 KDa
Cellular Localization Secreted, extracellular space, extracellular matrix (Probable).
Database Links
SwissProt ID P09237
Application

Application

Fig1: Sample: Uterus (Mouse) Lysate at 30 ug Primary: Anti- MMP-7 (ER1913-08) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 34 kD
Positive Control Mouse Uterus Lysate.
Application Notes WB:1:500-2000:
IHC-P:1:400-800:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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