Application
Fig1: Sample: Kidney(Mouse) Cell Lysate at 40 ug Primary: Anti-MPZL (ER1913-15) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 26 kD| Product Name | MPZL |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | immunoglobulin family transmembrane protein MPZL1 MPZL1b MPZL1_HUMAN myelin protein zero like 1 myelin protein zero like protein 1 precursor myelin protein zero like protein MPZL1b OTTHUMP00000032519 protein zero related PZR PZR1b PZRa PZRb. |
| Product description | Cell surface receptor, which is involved in signal transduction processes. Is a major receptor for concanavalin A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine protein kinases. Isoform 3 seems to block tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, unlike isoforms 2 and 3, may be involved in regulation of integrin mediated cell motility. |
| Immunogen | KLH conjugated synthetic peptide derived from human MPZL 61-160/269 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogCowHorseRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | immunoglobulin family transmembrane protein MPZL1 MPZL1b MPZL1_HUMAN myelin protein zero like 1 myelin protein zero like protein 1 precursor myelin protein zero like protein MPZL1b OTTHUMP00000032519 protein zero related PZR PZR1b PZRa PZRb. |
|---|---|
| Molecular Weight(MW) | 26 KDa |
| Cellular Localization | Membrane; single pass type I membrane protein (Potential) |
| SwissProt ID | O95297 |
|---|
Application
Fig1: Sample: Kidney(Mouse) Cell Lysate at 40 ug Primary: Anti-MPZL (ER1913-15) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 26 kD| Positive Control | Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbilical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
