Application
Fig1: Sample: HepG2 Cell (Human) Lysate at 30 ug Primary: Anti- NAV2 (ER1913-56) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 268kD Observed band size: 160kDApplication
Fig2: Sample: U251 Cell (Human) Lysate at 30 ug Primary: Anti- NAV2 (ER1913-56) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 268kD Observed band size: 160kD| Product Name | NAV2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HELAD1 Helicase, APC down regulated 1 KIAA1419 mCG 145366 mKIAA3015 NAV 2 Neuron navigator 2 POMFIL2 Pore membrane and/or filament interacting like protein 2 RAINB1 RAINB2 Retinoic acid inducible in neuroblastoma 1 Steerin 2 STEERIN2 Unc 53 homolog 2 Unc53H2 NAV2_HUMAN. |
| Product description | NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3' to 5' helicase activity and exonuclease activity and is involved in the development of different sensory organs. |
| Immunogen | KLH conjugated synthetic peptide derived from human NAV2/RAINB1 21-120/2488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseDogCowHorseRabbit |
| Concentration | 1mg/ml |
| Alternative Names | HELAD1
Helicase APC down regulated 1 KIAA1419 mCG 145366 mKIAA3015 NAV 2 Neuron navigator 2 POMFIL2 Pore membrane and/or filament interacting like protein 2 RAINB1 RAINB2 Retinoic acid inducible in neuroblastoma 1 Steerin 2 STEERIN2 Unc 53 homolog 2 Unc53H2 NAV2_HUMAN. |
|---|---|
| Molecular Weight(MW) | 268 KDa |
| Cellular Localization | Nuclear. |
| SwissProt ID | Q8IVL1 |
|---|
Application
Fig1: Sample: HepG2 Cell (Human) Lysate at 30 ug Primary: Anti- NAV2 (ER1913-56) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 268kD Observed band size: 160kD
Application
Fig2: Sample: U251 Cell (Human) Lysate at 30 ug Primary: Anti- NAV2 (ER1913-56) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 268kD Observed band size: 160kD| Positive Control | Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
