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OAT-3

Catalog Number:OM630590
OM630590
Discount Price
OM630590-100ul
1~2 Week
100ul
OM630590-50ul
50ul
OM630590-20ul
20ul
1~2 Week
Product Profile
Product Name OAT-3
Antibody Type Primary Antibodies
Antigen Alias Organic anion transporter 3 hOAT3 OAT3 SLC22A8 Solute carrier family 22 member 8 S22A8_RAT.
Product description Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Immunogen KLH conjugated synthetic peptide derived from rat OAT-3 31-110/536
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-2000:
Species Reactivity HumanMouseRatRabbit
Concentration 1mg/ml
Target Information
Alternative Names Organic anion transporter 3 hOAT3 OAT3 SLC22A8 Solute carrier family 22 member 8 S22A8_RAT.
Molecular Weight(MW) 59 KDa
Cellular Localization Basolateral cell membrane; Multi-pass membrane protein (Potential). Note=Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity).
Database Links
SwissProt ID Q8HY24
Application

Application

Fig1: Sample:Kidney (Mouse) Lysate at 40 ug Primary: Anti-OAT-3 (ER1914-28) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 59 kD Observed band size: 65 kD
Positive Control Expressed in kidney.
Application Notes WB:1:500-2000:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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