Application
Fig1: Sample: TT Cell (Human) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kDApplication
Fig2: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kDApplication
Fig3: Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kDApplication
Fig4: Sample: Heart (Rat) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kD| Product Name | OMA1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 2010001O09Rik DAB1 FLJ33782 Metalloendopeptidase OMA1 Metalloendopeptidase OMA1, mitochondrial Metalloprotease-related protein 1 mitochondrial MPRP 1 MPRP-1 MPRP1 OMA1 OMA1 homolog zinc metallopeptidase OMA1 homolog, zinc metallopeptidase (S. cerevisiae) OMA1 zinc metallopeptidase OMA1 zinc metallopeptidase homolog OMA1_HUMAN Overlapping activity with M-AAA protease Overlapping with the m-AAA protease 1 homolog peptidase YKR087C Zinc metallopeptidase OMA1 ZMPOMA1. |
| Product description | Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. |
| Immunogen | KLH conjugated synthetic peptide derived from human OMA1 401-500/524 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatChickenPigCowHorseRabbitZebra FishCat |
| Concentration | 1mg/ml |
| Alternative Names | 2010001O09Rik
DAB1
FLJ33782
Metalloendopeptidase OMA1
Metalloendopeptidase OMA1 mitochondrial Metalloprotease-related protein 1 mitochondrial MPRP 1 MPRP-1 MPRP1 OMA1 OMA1 homolog zinc metallopeptidase OMA1 homolog zinc metallopeptidase (S. cerevisiae) OMA1 zinc metallopeptidase OMA1 zinc metallopeptidase homolog OMA1_HUMAN Overlapping activity with M-AAA protease Overlapping with the m-AAA protease 1 homolog peptidase YKR087C Zinc metallopeptidase OMA1 ZMPOMA1. |
|---|---|
| Molecular Weight(MW) | 60 KDa |
| Cellular Localization | Mitochondrion membrane. |
| SwissProt ID | Q96E52 |
|---|
Application
Fig1: Sample: TT Cell (Human) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kD
Application
Fig2: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kD
Application
Fig3: Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kD
Application
Fig4: Sample: Heart (Rat) Lysate at 40 ug Primary: Anti- OMA1 (ER1914-36) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 55 kD| Positive Control | Widely expressed, with strong expression in the heart, skeletal muscle, kidney and liver. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
