Application
Fig1: Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Plasminogen (ER1915-13) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53/87 kD Observed band size: 53 kD| Product Name | Plasminogen |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Plasminogen Angiostatin DKFZp779M0222 Microplasmin Plasmin Plasmin heavy chain A PLG PLMN_HUMAN. |
| Product description | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. |
| Immunogen | KLH conjugated synthetic peptide derived from human PLG 251-350/810 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigCow |
| Concentration | 1mg/ml |
| Alternative Names | Plasminogen Angiostatin DKFZp779M0222 Microplasmin Plasmin Plasmin heavy chain A PLG PLMN_HUMAN. |
|---|---|
| Molecular Weight(MW) | 53/87 KDa |
| Cellular Localization | Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface. |
| SwissProt ID | P00747 |
|---|
Application
Fig1: Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-Plasminogen (ER1915-13) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53/87 kD Observed band size: 53 kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
