Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-PPP2R5C (ER1915-35) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 52 kD| Product Name | PPP2R5C |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 2A5G_HUMAN B' alpha regulatory subunit B56G KIAA0044 MGC23064 PP2A B subunit B' gamma isoform PP2A B subunit B56 gamma isoform PP2A B subunit isoform B''-gamma PP2A B subunit isoform B56-gamma PP2A B subunit isoform PR61-gamma PP2A B subunit isoform R5-gamma PP2A B subunit PR61 gamma isoform PP2A B subunit R5 gamma isoform Ppp2r5c PR61G Protein phosphatase 2 regulatory subunit B (B56) gamma isoform Protein phosphatase 2 regulatory subunit B' gamma Renal carcinoma antigen NY REN 29 Renal carcinoma antigen NY-REN-29 Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform 2A5G_HUMAN. |
| Product description | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation. |
| Immunogen | KLH conjugated synthetic peptide derived from human PPP2R5C 390-435/524 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogCowHorseRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | 2A5G_HUMAN B' alpha regulatory subunit B56G KIAA0044 MGC23064 PP2A B subunit B' gamma isoform PP2A B subunit B56 gamma isoform PP2A B subunit isoform B''-gamma PP2A B subunit isoform B56-gamma PP2A B subunit isoform PR61-gamma PP2A B subunit isoform R5-gamma PP2A B subunit PR61 gamma isoform PP2A B subunit R5 gamma isoform Ppp2r5c PR61G Protein phosphatase 2 regulatory subunit B (B56) gamma isoform Protein phosphatase 2 regulatory subunit B' gamma Renal carcinoma antigen NY REN 29 Renal carcinoma antigen NY-REN-29 Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform 2A5G_HUMAN. |
|---|---|
| Molecular Weight(MW) | 61 KDa |
| Cellular Localization | Nucleus. Chromosome. centromere. |
| SwissProt ID | Q13362 |
|---|
Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-PPP2R5C (ER1915-35) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 52 kD| Positive Control | Highest levels in heart, skeletal muscle and brain. Lower levels in pancreas, kidney, lung and placenta. Very low levels in liver. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
