| Product Name | SH3PX1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MST 155 MST155 MSTP 155 MSTP155 OTTHUMP00000040083 Protein SDP 1 Protein SDP1 SDP 1 SDP1 SH3 and PX domain containing protein 3A SH3 and PX domain containing protein SH3PX1 SH3 and PX domain-containing protein 1 SH3 and PX domain-containing protein 3A SH3PX1 SH3PXD3A SNX 9 SNX9 SNX9_HUMAN Sorting nexin 9 Sorting nexin-9 WASP interactor protein Wiskott Aldrich syndrome protein (WASP) interactor protein Wiskott Aldrich syndrome protein interactor protein WISP. |
| Product description | May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate. |
| Immunogen | KLH conjugated synthetic peptide derived from human SNX5 501-595/595 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigCowHorse |
| Concentration | 1mg/ml |
| Alternative Names | MST 155 MST155 MSTP 155 MSTP155 OTTHUMP00000040083 Protein SDP 1 Protein SDP1 SDP 1 SDP1 SH3 and PX domain containing protein 3A SH3 and PX domain containing protein SH3PX1 SH3 and PX domain-containing protein 1 SH3 and PX domain-containing protein 3A SH3PX1 SH3PXD3A SNX 9 SNX9 SNX9_HUMAN Sorting nexin 9 Sorting nexin-9 WASP interactor protein Wiskott Aldrich syndrome protein (WASP) interactor protein Wiskott Aldrich syndrome protein interactor protein WISP. |
|---|---|
| Molecular Weight(MW) | 67 KDa |
| Cellular Localization | Cytoplasmic vesicle membrane. Cell membrane. Cytoplasmic vesicle > clathrin-coated vesicle. Golgi apparatus > trans-Golgi network. Cell projection > ruffle. Cytoplasm. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. Colocalizes with the actin cytoskeleton at the cell membrane. |
| SwissProt ID | Q9Y5X1 |
|---|
| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
