Application
Fig1: Protein: HepG2(human) lysate at 40ug; Primary: rabbit Anti-SIGLEC11 (ER1916-60) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 74 kD Observed band size: 74 kD| Product Name | SIGLEC11 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | sialic acid binding Ig like lectin 11 sialic acid binding lectin 11 Siglec 11 SIG11_HUMAN. |
| Product description | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| Immunogen | KLH conjugated synthetic peptide derived from human SIGLEC11 251-350/698 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | sialic acid binding Ig like lectin 11 sialic acid binding lectin 11 Siglec 11 SIG11_HUMAN. |
|---|---|
| Molecular Weight(MW) | 74 KDa |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| SwissProt ID | Q96RL6 |
|---|
Application
Fig1: Protein: HepG2(human) lysate at 40ug; Primary: rabbit Anti-SIGLEC11 (ER1916-60) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 74 kD Observed band size: 74 kD| Positive Control | Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
