Application
Fig1: Sample: Embryo (Mouse) Lysate at 40 ug Primary: Anti-SLC17A5(ER1916-68) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 129 kD Observed band size: 129 kD| Product Name | SLC17A5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AST H(+)/nitrate cotransporter H(+)/sialic acid cotransporter ISSD Membrane glycoprotein HP59 NSD S17A5_MOUSE SD Sialic acid storage disease Sialin SIASD Slc17a5 SLD Solute carrier family 17 (anion/sugar transportermember 5 Solute carrier family 17 member 5 Vesicular H(+)/Aspartate-glutamate cotransporter. |
| Product description | Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential-dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed and secreted in saliva. |
| Immunogen | KLH conjugated synthetic peptide derived from mouse SLC17A5 201-300/495 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | MouseRatCowRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | AST H(+)/nitrate cotransporter H(+)/sialic acid cotransporter ISSD Membrane glycoprotein HP59 NSD S17A5_MOUSE SD Sialic acid storage disease Sialin SIASD Slc17a5 SLD Solute carrier family 17 (anion/sugar transportermember 5 Solute carrier family 17 member 5 Vesicular H(+)/Aspartate-glutamate cotransporter. |
|---|---|
| Molecular Weight(MW) | 56 KDa |
| Cellular Localization | Cell membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Lysosome membrane. |
| SwissProt ID | Q8BN82 |
|---|
Application
Fig1: Sample: Embryo (Mouse) Lysate at 40 ug Primary: Anti-SLC17A5(ER1916-68) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 129 kD Observed band size: 129 kD| Positive Control | Found in fetal lung and small intestine, and at lower level in fetal skin and muscle. In the adult, detected in placenta, kidney and pancreas. Abundant in the endothelial cells of tumors from ovary, colon, breast and lung, but is not detected in endothelial cells from the corresponding normal tissues. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
