Application
Fig1: Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-SMCR7L (ER1916-90) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD| Product Name | SMCR7L |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | dJ1104E15.3 HSU79252 Hypothetical protein LOC54471 MID51 MIEF1 mitochondrial dynamic protein MID51 mitochondrial dynamic protein of 51 kDa mitochondrial dynamics protein MID51 mitochondrial dynamics protein of 51 kDa mitochondrial elongation factor 1 SMC7L_HUMAN SMCR7-like protein Smcr7l Smith Magenis syndrome chromosome region candidate gene 7 protein like Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like Smith-Magenis syndrome chromosome region, candidate 7-like. |
| Product description | Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. |
| Immunogen | KLH conjugated synthetic peptide derived from human SMCR7L 201-300/463 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatChickenPigCowHorseRabbitZebra FishSheep |
| Concentration | 1mg/ml |
| Alternative Names | dJ1104E15.3
HSU79252
Hypothetical protein LOC54471
MID51
MIEF1
mitochondrial dynamic protein MID51
mitochondrial dynamic protein of 51 kDa
mitochondrial dynamics protein MID51
mitochondrial dynamics protein of 51 kDa
mitochondrial elongation factor 1
SMC7L_HUMAN
SMCR7-like protein
Smcr7l
Smith Magenis syndrome chromosome region candidate gene 7 protein like
Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like
Smith-Magenis syndrome chromosome region candidate 7-like. |
|---|---|
| Molecular Weight(MW) | 51 KDa |
| Cellular Localization | Membrane. |
| SwissProt ID | Q9NQG6 |
|---|
Application
Fig1: Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-SMCR7L (ER1916-90) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD| Positive Control | Expression is relatively high in heart, skeletal muscle, pancreas and kidney. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
