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TGF beta Receptor I

Catalog Number:OM630920
OM630920
Discount Price
OM630920-100ul
1~2 Week
100ul
OM630920-50ul
50ul
OM630920-20ul
20ul
1~2 Week
Product Profile
Product Name TGF beta Receptor I
Antibody Type Primary Antibodies
Antigen Alias TGFBR1 TGF Beta R1 TGF beta Receptor I AAT 5 AAT5 Activin A receptor type II like kinase 53kDa Activin receptor like kinase 5 ACVRLK 4 ACVRLK4 ALK 5 ALK5 Serine/threonine protein kinase receptor R4 SKR 4 SKR4 TbetaR I TGF beta receptor type 1 TGF beta receptor type I TGF beta type I receptor TGFBR 1 TGFBR1 protein TGFR 1 TGFR1 Transforming growth factor beta receptor I
Product description On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Immunogen KLH conjugated synthetic peptide derived from human TGF-beta R1 301-400/501
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC-PICC/IF
WB:1:500-2000:
IHC-P:1:400-800:
IF:1:100-500:
Species Reactivity HumanMouseRatCow
Concentration 1mg/ml
Target Information
Alternative Names TGFBR1 TGF Beta R1 TGF beta Receptor I AAT 5 AAT5 Activin A receptor type II like kinase 53kDa Activin receptor like kinase 5 ACVRLK 4 ACVRLK4 ALK 5 ALK5 Serine/threonine protein kinase receptor R4 SKR 4 SKR4 TbetaR I TGF beta receptor type 1 TGF beta receptor type I TGF beta type I receptor TGFBR 1 TGFBR1 protein TGFR 1 TGFR1 Transforming growth factor beta receptor I
Molecular Weight(MW) 55 KDa
Cellular Localization Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction.
Database Links
SwissProt ID P36897
Application

Application

Fig1: Sample: Lane 1: Gastric carcinoma(Human) Lysate at 30 ug Lane 2:Stomach (Mouse) Lysate at 30 ug Primary: Anti-TGF Beta R1/TGFBR1 (ER1917-65) at 1:200 dilution; Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000 dilution; Predicted band size : 55kD Observed band size : 55kD

Application

Fig2: Sample: Small intestine (Mouse) Lysate at 30 ug Primary: Anti- TGF beta Receptor 1 (ER1917-65) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD

Application

Fig3: Sample: 293T(Human) Cell Lysate at 40 ug A431(Human) Cell Lysate at 40 ug Primary: Anti-TGF beta Receptor I (bs-10196R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
Positive Control Found in all tissues examined, most abundant in placenta and least abundant in brain and heart.
Application Notes WB:1:500-2000:
IHC-P:1:400-800:
IF:1:100-500:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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