Listeria induced
A20-binding inhibitor of NF-kappa-B activation 3
ABIN-3
ABIN-3 beta
FLJ21162
LIND
Listeria induced gene protein
TNFAIP3 interacting protein 3
TNFAIP3-interacting protein 3 beta
TNIP3
TNIP3 beta
TNIP3_HUMAN.
Product description
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Immunogen
KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3 51-150/325
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRatCowSheep
Concentration
1mg/ml
Target Information
Alternative Names
Listeria induced
A20-binding inhibitor of NF-kappa-B activation 3
ABIN-3
ABIN-3 beta
FLJ21162
LIND
Listeria induced gene protein
TNFAIP3 interacting protein 3
TNFAIP3-interacting protein 3 beta
TNIP3
TNIP3 beta
TNIP3_HUMAN.
Fig1: Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- TNFAIP3 interacting protein 3 (ER1917-86) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kD
Observed band size: 39 kD
Positive Control
Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.