Tumor necrosis factor ligand superfamily member 18
AITRL
GITRL
hGITRL
TL6
Activation inducible TNF related ligand
AITR ligand
AITRL
GITR ligand
Glucocorticoid induced TNF related ligand
Glucocorticoid induced TNFR related protein ligand
MGC138237
Tumor necrosis factor (ligand) superfamily member 18
GITR Ligand
TNF18_HUMAN.
Product description
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.
Immunogen
KLH conjugated synthetic peptide derived from human TNFSF18 101-199/199
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
Tumor necrosis factor ligand superfamily member 18
AITRL
GITRL
hGITRL
TL6
Activation inducible TNF related ligand
AITR ligand
AITRL
GITR ligand
Glucocorticoid induced TNF related ligand
Glucocorticoid induced TNFR related protein ligand
MGC138237
Tumor necrosis factor (ligand) superfamily member 18
GITR Ligand
TNF18_HUMAN.
Molecular Weight(MW)
23 KDa
Cellular Localization
Cell membrane; Single-pass type II membrane protein.
Fig1: Sample:
Testis (Mouse) Lysate at 40 ug
Primary: Anti-TNFSF18 (ER1917-91) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 29 kD
Positive Control
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.