| Product Name | Ube2L3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | E2 F1 E2-F1 L UBC L-UBC UB2L3_HUMAN UBCE7 UbcH7 UbcM4 Ube2l3 Ubiquitin carrier protein L3 Ubiquitin conjugating enzyme E2 L3 Ubiquitin protein ligase L3 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2-F1 Ubiquitin-protein ligase L3. |
| Product description | Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis. |
| Immunogen | KLH conjugated synthetic peptide derived from human Ube2L3 81-154/154 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatCowHorseRabbitZebra FishSheep |
| Concentration | 1mg/ml |
| Alternative Names | E2 F1 E2-F1 L UBC L-UBC UB2L3_HUMAN UBCE7 UbcH7 UbcM4 Ube2l3 Ubiquitin carrier protein L3 Ubiquitin conjugating enzyme E2 L3 Ubiquitin protein ligase L3 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2-F1 Ubiquitin-protein ligase L3. |
|---|---|
| Molecular Weight(MW) | 18 KDa |
| Cellular Localization | Nucleus. Cytoplasm. |
| SwissProt ID | P68036 |
|---|
| Positive Control | Ubiquitous, with highest expression in testis. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
