Application
Fig1: Protein: line1,Raji lysate;line2,mouse spleen lysate; Primary: rabbit Anti-ZNT8 (ER1919-18) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 41 kD Observed band size: 41 kD| Product Name | ZNT8 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC30A8 solute carrier family 30 (zinc transporter), member 8 Solute carrier family 30 member 8 Zinc transporter 8 zinc transporter ZnT-8 ZnT-8 ZNT 8 ZNT8_HUMAN. |
| Product description | Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNT8 101-200/369 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigSheep |
| Concentration | 1mg/ml |
| Alternative Names | SLC30A8
solute carrier family 30 (zinc transporter) member 8 Solute carrier family 30 member 8 Zinc transporter 8 zinc transporter ZnT-8 ZnT-8 ZNT 8 ZNT8_HUMAN. |
|---|---|
| Molecular Weight(MW) | 41 KDa |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (Probable). Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein (Probable). Note=Associated with insulin and glucagon secretory granules (By similarity). |
| SwissProt ID | Q8IWU4 |
|---|
Application
Fig1: Protein: line1,Raji lysate;line2,mouse spleen lysate; Primary: rabbit Anti-ZNT8 (ER1919-18) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 41 kD Observed band size: 41 kD| Positive Control | In the endocrine pancreas, expressed in insulin-producing beta cells. Expressed at relatively high levels in subcutaneous fat tissue from lean persons; much lower levels in visceral fat, whether from lean or obese individuals, and in subcutaneous fat tissue from obese individuals. Expressed in peripheral blood mononuclear cells, including T-cells and B-cells, with great variation among individuals ranging from negative to strongly positive. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
