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TGF-Beta 1

Catalog Number:OM631083
OM631083
Discount Price
OM631083-100ul
1~2 Week
100ul
OM631083-50ul
50ul
OM631083-20ul
20ul
1~2 Week
Product Profile
Product Name TGF-Beta 1
Antibody Type Primary Antibodies
Antigen Alias Cartilage-inducing factor antibody CED antibody Differentiation inhibiting factor antibody DPD1 antibody LAP antibody Latency-associated peptide antibody Prepro transforming growth factor beta 1 antibody TGF beta 1 antibody TGF beta antibody TGF beta 1 protein antibody TGF-beta 1 protein antibody TGF-beta-1 antibody TGF-beta-5 antibody TGF-beta1 antibody TGFB antibody Tgfb-1 antibody tgfb1 antibody TGFB1_HUMAN antibody TGFbeta antibody TGFbeta1 antibody Transforming Growth Factor b1 antibody Transforming Growth Factor beta 1 antibody Transforming growth factor beta 1a antibody transforming growth factor beta-1 antibody transforming growth factor, beta 1 antibody Transforming Growth Factor-?1 antibody
Product description Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN. Function: TGF beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. Tissue specificity: TGF beta 1 is highly expressed in bone. A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly.
Immunogen peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCIHCFC
WB:1:500-1:1,000
ICC:1:200
IHC:1:200
FC:1:100:
Species Reactivity HumanMouseRatZebra Fish
Concentration 1mg/ml
Target Information
Alternative Names Cartilage-inducing factor antibody CED antibody Differentiation inhibiting factor antibody DPD1 antibody LAP antibody Latency-associated peptide antibody Prepro transforming growth factor beta 1 antibody TGF beta 1 antibody TGF beta antibody TGF beta 1 protein antibody TGF-beta 1 protein antibody TGF-beta-1 antibody TGF-beta-5 antibody TGF-beta1 antibody TGFB antibody Tgfb-1 antibody tgfb1 antibody TGFB1_HUMAN antibody TGFbeta antibody TGFbeta1 antibody Transforming Growth Factor b1 antibody Transforming Growth Factor beta 1 antibody Transforming growth factor beta 1a antibody transforming growth factor beta-1 antibody transforming growth factor
beta 1 antibody Transforming Growth Factor-?1 antibody
Molecular Weight(MW) 44 kDa
Cellular Localization Secreted
Database Links
SwissProt ID P01137
Application

Application

Fig1: Western blot analysis of TGF-Beta 1 on different cell lysates using anti- TGF-Beta 1 antibody at 1/1000 dilution. Positive control: Lane 1: Raji Lane 2: MCF-2 Lane 3: A549 Lane 4: Human kidney

Application

Fig2: ICC staining TGF-Beta 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining TGF-Beta 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: ICC staining TGF-Beta 1 in SKBR-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TGF-Beta 1 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TGF-Beta 1 antibody. Counter stained with hematoxylin.

Application

Fig7: Flow cytometric analysis of HepG2 cells with TGF-Beta 1 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.
Positive Control Raji, MCF-7, A549, human kidney tissue, mouse kidney tissue, SKBR-3, Hela, HepG2
Application Notes WB:1:500-1:1,000
ICC:1:200
IHC:1:200
FC:1:100:
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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