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STAT6

Catalog Number:OM631095
OM631095
Discount Price
OM631095-100ul
1~2 Week
100ul
OM631095-50ul
50ul
OM631095-20ul
20ul
1~2 Week
Product Profile
Product Name STAT6
Antibody Type Primary Antibodies
Antigen Alias 12S1644 antibody D12S1644 antibody IL 4 STAT antibody IL-4 Stat antibody IL4 STAT antibody Interleukin 4 Induced antibody Interleukin 4 Induced Transcription Factor IL4 STAT antibody Signal transducer and activator of transcription 6 antibody Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody Signal transducer and activator of transcription 6, interleukin 4 induced antibody STAT 6 antibody STAT interleukin4 induced antibody STAT, interleukin4 induced antibody Stat6 antibody STAT6_HUMAN antibody STAT6B antibody STAT6C antibody Transcription factor IL 4 STAT antibody
Product description In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
Immunogen peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCIHCFC
WB:1:1,000
ICC:1:200
IHC:1:200
FC:1:100-1:200
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names 12S1644 antibody D12S1644 antibody IL 4 STAT antibody IL-4 Stat antibody IL4 STAT antibody Interleukin 4 Induced antibody Interleukin 4 Induced Transcription Factor IL4 STAT antibody Signal transducer and activator of transcription 6 antibody Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody Signal transducer and activator of transcription 6
interleukin 4 induced antibody STAT 6 antibody STAT interleukin4 induced antibody STAT
interleukin4 induced antibody Stat6 antibody STAT6_HUMAN antibody STAT6B antibody STAT6C antibody Transcription factor IL 4 STAT antibody
Molecular Weight(MW) 94 kDa
Cellular Localization Cytoplasm, nucleus.
Database Links
SwissProt ID P42226
Application

Application

Fig1: Western blot analysis of STAT6 on different cell lysates using anti-STAT6 antibody at 1/1000 dilution. Positive control: Lane 1: Raji Lane 2: Daudi Lane 3: Hela Lane 4: Ags Lane 5: Jurkat

Application

Fig2: ICC staining STAT6 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig6: Flow cytometric analysis of Hela cells with ATAT6 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.
Positive Control Jurkat, Raji, Daudi, Hela, Ags, human tosnsil tissue, human kidney tissue, human gastric carcinoma tissue.
Application Notes WB:1:1,000
ICC:1:200
IHC:1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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