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Chromogranin A

Catalog Number:OM631103
OM631103
Discount Price
OM631103-100ul
1~2 Week
100ul
OM631103-50ul
50ul
OM631103-20ul
20ul
1~2 Week
Product Profile
Product Name Chromogranin A
Antibody Type Primary Antibodies
Antigen Alias CISY_HUMAN antibody Citrate synthase antibody Citrate synthase, mitochondrial antibody citrate synthetase antibody Cs antibody EC 2.3.3 antibody EC 2.3.3.1 antibody
Product description Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.
Immunogen peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:2,000
IHC:1:200
FC:1:100-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names CISY_HUMAN antibody Citrate synthase antibody Citrate synthase
mitochondrial antibody citrate synthetase antibody Cs antibody EC 2.3.3 antibody EC 2.3.3.1 antibody
Molecular Weight(MW) 86 kDa
Cellular Localization Cytoplasmic vesicle, secreted.
Database Links
SwissProt ID P26339
Application

Application

Fig1: Western blot analysis of chromogranin A on PC12 cell lysates using anti-chromogranin A antibody at 1/2000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using anti-chromogranin A antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-chromogranin A antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-chromogranin A antibody. Counter stained with hematoxylin.

Application

Fig5: Flow cytometric analysis of Lovo cells with chromogranin A antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.
Positive Control PC12, Lovo, mouse pancreas tissue, rat pancreas tissue, human colon cancer tissue.
Application Notes WB:1:2,000
IHC:1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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