Application
Fig1: ICC staining MATER in mouse blastocyst and 2-cell stage embryo (red). Cells were incubated overnight at 4| Product Name | MATER |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLR19.8 antibody MATER antibody Mater protein homolog antibody Maternal antigen that embryos require antibody NACHT, leucine rich repeat and PYD containing 5 antibody NACHT, LRR and PYD domains-containing protein 5 antibody NALP5_HUMAN antibody NLR family, pyrin domain containing 5 antibody NLRP5 antibody Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 antibody PAN11 antibody PYPAF8 antibody |
| Product description | NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC |
| ICC:1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CLR19.8 antibody
MATER antibody
Mater protein homolog antibody
Maternal antigen that embryos require antibody
NACHT leucine rich repeat and PYD containing 5 antibody NACHT LRR and PYD domains-containing protein 5 antibody NALP5_HUMAN antibody NLR family pyrin domain containing 5 antibody NLRP5 antibody Nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain containing 5 antibody PAN11 antibody PYPAF8 antibody |
|---|---|
| Molecular Weight(MW) | 134 kDa |
| Cellular Localization | Cytoplasm, nucleus, mitochondrion. |
| SwissProt ID | P59047 |
|---|
Application
Fig1: ICC staining MATER in mouse blastocyst and 2-cell stage embryo (red). Cells were incubated overnight at 4| Positive Control | Mouse blastocyst, mouse embryo. |
|---|---|
| Application Notes | ICC:1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
