Application
Fig1: Western blot analysis of Kanadaptin on HUVEC cells lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (ER60003, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.| Product Name | Kanadaptin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ10624 antibody FLJ41004 antibody HLC-3 antibody HLC3 antibody Human lung cancer oncogene 3 protein antibody Kanadaptin antibody Kidney anion exchanger adapter protein antibody Kidney anion exchanger adaptor protein antibody Lung cancer oncogene 3 protein antibody MGC120646 antibody MGC120648 antibody NADAP_HUMAN antibody SLC4A1AP antibody Solute carrier family 4 (anion exchanger) member 1 adaptor protein antibody Solute carrier family 4 anion exchanger member 1 adapter protein antibody |
| Product description | Solute carrier family 4 anion exchanger member 1 adapter protein (SLC4A1AP), also designated Kanadaptin or human lung cancer oncogene 3 protein (HLC-3), is a 796 amino acid protein that is widely expressed in many tissues, including kidney, lung, liver, brain and skeletal and cardiac muscle. SLC4A1AP is a multidomain protein that localizes to the nucleus where it may play a role in signaling. SLC4A1AP was previously thought to act as an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane. However, recent studies suggest SLC4A1AP does not interact with kAE1. The gene encoding SLC4A1AP maps to chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Kanadaptin. AA range:421-470 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC-PIF |
| WB:1:500-1:2000 IHC-P:1:50-1:200 IF: 1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | FLJ10624 antibody
FLJ41004 antibody
HLC-3 antibody HLC3 antibody Human lung cancer oncogene 3 protein antibody Kanadaptin antibody Kidney anion exchanger adapter protein antibody Kidney anion exchanger adaptor protein antibody Lung cancer oncogene 3 protein antibody MGC120646 antibody MGC120648 antibody NADAP_HUMAN antibody SLC4A1AP antibody Solute carrier family 4 (anion exchanger) member 1 adaptor protein antibody Solute carrier family 4 anion exchanger member 1 adapter protein antibody |
|---|---|
| Molecular Weight(MW) | 85 kDa |
| Cellular Localization | Nucleus. Cytoplasm. |
| SwissProt ID | Q9BWU0 |
|---|
Application
Fig1: Western blot analysis of Kanadaptin on HUVEC cells lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (ER60003, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.| Positive Control | HUVEC cells. |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC-P:1:50-1:200 IF: 1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
