| Product Name | Cleaved-Bad (D71) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BAD antibody; BBC6 antibody; BCL2L8 antibody; Bcl2 antagonist of cell death antibody; BAD antibody; Bcl-2-binding component 6 antibody; Bcl-2-like protein 8 antibody; Bcl2-L-8 antibody; Bcl-XL/Bcl-2-associated death promoter antibody; |
| Product description | BCL2 associated agonist of cell death encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of BCL2 associated agonist of cell death. Alternative splicing of BAD results in two transcript variants which encode the same isoform. |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse BAD. AA range:21-70 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BAD antibody BBC6 antibody BCL2L8 antibody Bcl2 antagonist of cell death antibody BAD antibody Bcl-2-binding component 6 antibody Bcl-2-like protein 8 antibody Bcl2-L-8 antibody Bcl-XL/Bcl-2-associated death promoter antibody |
|---|---|
| Molecular Weight(MW) | 20 kDa |
| Cellular Localization | Mitochondrion outer membrane, Cytoplasm. |
| SwissProt ID | Q61337 |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
