| Product Name | Cleaved-Factor XIIIa (G39) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | F13A1 antibody; F13A antibody; Coagulation factor XIII A chain antibody; Coagulation factor XIIIa antibody; Protein-glutamine gamma-glutamyltransferase A chain antibody; Transglutaminase A chain antibody; |
| Product description | This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FA13A. AA range:20-69 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | F13A1 antibody F13A antibody Coagulation factor XIII A chain antibody Coagulation factor XIIIa antibody Protein-glutamine gamma-glutamyltransferase A chain antibody Transglutaminase A chain antibody |
|---|---|
| Molecular Weight(MW) | 79 kDa |
| Cellular Localization | Cytoplasm, Secreted. |
| SwissProt ID | P00488 |
|---|
| Positive Control | Brain,Pancreas,Plasma, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
