| Product Name | Cleaved-Notch 2 (V1697) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NOTCH2 antibody; Neurogenic locus notch homolog protein 2 antibody; Notch 2 antibody; hN2 antibody; |
| Product description | This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NOTCH2. AA range:1678-1727 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | NOTCH2 antibody Neurogenic locus notch homolog protein 2 antibody Notch 2 antibody hN2 antibody |
|---|---|
| Molecular Weight(MW) | 83 kDa |
| Cellular Localization | Cell membrane, Nucleus, Cytoplasm. |
| SwissProt ID | Q04721 |
|---|
| Positive Control | Brain,Epithelium,Mammary tumor,Placenta,T-cell,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
