| Product Name | Cleaved-Plasma Kallikrein HC (R390) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KLKB1 antibody; KLK3 antibody; Plasma kallikrein antibody; Fletcher factor antibody; Kininogenin antibody; Plasma prekallikrein antibody; |
| Product description | This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KLKB1 antibody KLK3 antibody Plasma kallikrein antibody Fletcher factor antibody Kininogenin antibody Plasma prekallikrein antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Secreted |
| SwissProt ID | P03952 |
|---|
| Positive Control | Colon,Liver,Plasma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
