| Product Name | E2F-4 (Acetyl Lys96) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | E2F4 antibody; Transcription factor E2F4 antibody; E2F-4 antibody; |
| Product description | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge |
| Immunogen | The antiserum was produced against synthesized Acetyl-peptide derived from human E2F4 around the Acetylation site of Lys96. AA range:61-110 |
| Modification | Acetyl Lys96 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | E2F4 antibody Transcription factor E2F4 antibody E2F-4 antibody |
|---|---|
| Molecular Weight(MW) | 43 kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | Q16254 |
|---|
| Positive Control | Cervix carcinoma,Colon carcinoma,Kidney, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
