| Product Name | AMPKβ2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRKAB2 antibody; 5'-AMP-activated protein kinase subunit beta-2 antibody; AMPK subunit beta-2 antibody; |
| Product description | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. |
| Immunogen | Recombinant Protein of AMPKβ2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PRKAB2 antibody 5'-AMP-activated protein kinase subunit beta-2 antibody AMPK subunit beta-2 antibody |
|---|---|
| Molecular Weight(MW) | 30 kDa |
| SwissProt ID | O43741 |
|---|
| Positive Control | Liver,Pancreas, |
|---|---|
| Application Notes | WB:1:1000-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
