| Product Name | GABA A Receptor α4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GABRA4 antibody; Gamma-aminobutyric acid receptor subunit alpha-4 antibody; GABA(A) receptor subunit alpha-4 antibody; |
| Product description | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene., |
| Immunogen | Synthetic Peptide of GABA A Receptor α4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000-1:2000 IHC:1:100-200 |
|
| Species Reactivity | HumanRatMouse |
| Concentration | 1mg/ml |
| Alternative Names | GABRA4 antibody Gamma-aminobutyric acid receptor subunit alpha-4 antibody GABA(A) receptor subunit alpha-4 antibody |
|---|---|
| Molecular Weight(MW) | 62 kDa |
| SwissProt ID | P48169 |
|---|
| Positive Control | Brain,Brain cortex, |
|---|---|
| Application Notes | WB:1:1000-1:2000 IHC:1:100-200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
