| Product Name | GLP1R |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLP1R antibody; Glucagon-like peptide 1 receptor antibody; GLP-1 receptor antibody; GLP-1-R antibody; GLP-1R antibody; |
| Product description | This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen | Synthetic Peptide of GLP1R |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:1000 IHC:1:50-100 |
|
| Species Reactivity | HumanRatMouse |
| Concentration | 1mg/ml |
| Alternative Names | GLP1R antibody Glucagon-like peptide 1 receptor antibody GLP-1 receptor antibody GLP-1-R antibody GLP-1R antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa |
| SwissProt ID | P43220 |
|---|
| Positive Control | Gastric carcinoma,Insulinoma,Pancreas,Pancreatic islet,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:1000 IHC:1:50-100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
