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PCBP2

Catalog Number:OM631297
OM631297
Discount Price
OM631297-100ul
1~2 Week
100ul
OM631297-50ul
50ul
OM631297-20ul
20ul
1~2 Week
Product Profile
Product Name PCBP2
Antibody Type Primary Antibodies
Product description

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate

Immunogen Synthesized peptide derived from human protein . at AA range: 30-110
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-1:2000
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Molecular Weight(MW) 40 kDa
Database Links
SwissProt ID Q15366
Application

WB

(h, i) Co-IP with anti-PCBP2 antibody as the precipitation antibody to detect the UCHL5 level after overexpressing MAFG-AS1 in T24/RT4 cells. (j) Co-IP with anti-PCBP2 antibody as the precipitating antibody to detect the amount of ubiquitin bound to PCBP2 after overexpression MAFG-AS1 and/or knocking down UCHL5 in T24/RT4 cells.
Positive Control Brain,Breast,Epithelium,Eye,Fetal brain cortex,Lung,Synovial membrane tissu
Application Notes WB:1:500-1:2000
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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References(1)