May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis. Belongs to the vinculin/alpha-catenin family. subunit:Interacts with ARHGEF1. tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230