| Product Name | NU2M |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol. disease:Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. disease:Defects in MT-ND2 may be associated with mitochondrial susceptibility to Alzheimer disease (AD). Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I subunit 2 family. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 40-120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 38 kDa |
|---|
| SwissProt ID | P03891 |
|---|
| Positive Control | Blood,Bone fossil,Bones,Breast cancer,Distant normal tissue,Glioma,Para-cancerous normal tissue,Pla |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
