| Product Name | PPIG |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0). domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II. enzyme regulation:Cyclosporin A (CsA)-sensitive. PPIases accelerate the folding of proteins. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the cyclophilin-type PPIase family. Contains 1 PPIase cyclophilin-type domain. subcellular location:Colocalizes with RNA splicing factors at nuclear speckles. subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II. tissue specificity:Ubiquitous. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 290-370 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanRatMouse |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 82 kDa |
|---|
| SwissProt ID | Q13427 |
|---|
| Positive Control | B-cell,Cervix,Epithelium,PCR rescued clones,Skin,T-cell,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
