| Product Name | RPGF6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Contains 1 cyclic nucleotide-binding domain. Contains 1 N-terminal Ras-GEF domain. Contains 1 PDZ (DHR) domain. Contains 1 Ras-associating domain. Contains 1 Ras-GEF domain. subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane. subunit:Interacts with the second PDZ domain of human PTP1e. tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 460-540 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 176 kDa |
|---|
| SwissProt ID | Q8TEU7 |
|---|
| Positive Control | Brain,Clones donated by RIKEN,Epithelium,Fetal brain,PCR re |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
